REJENERATİF PULPA TEDAVİLERİNE GENEL BİR BAKIŞ-A GENERAL OUTLOOK TO REGENERATIVE PULP THERAPY

Kübra TONGUÇ ALTIN, Elif SUNGURTEKİN EKÇİ, Elif Beril GÜRDOĞAN, Dilşad ŞENÖZ
2.035 338

Abstract


Özet

Son 10 yıl içerisinde, kök hücre biyolojisi ve doku mühendisliği üzerine yapılan çalışmalar diş hekimliği alanını olumlu bir yönde etkilemiştir. Rejeneratif endodontik tedavinin amacı, sağlıklı ve fonksiyonel bir dentin-pulpa komplesinin yeniden oluşturulmasıdır. Mineral trioksit agregat (MTA) gibi başarı gösteren materyallerin ve doku mühendisliği konseptlerinin kullanılması ile kök gelişimini tamamlamamış nekroze dişlerin kök-çevre doku gelişimlerinin devam etmesi mümkün olmuştur. Kök hücreler ile yapılan çalışmalarda umut vaat eden sonuçlar elde edilmiş olup halen diş-çevre dokularının rejenerasyonunda olumlu gelişmeler kaydedilmektedir. Kök hücrelerin kullanımı etik olarak sorgulandığından, bu materyallerin klinik olarak etkisi henüz bilinmemektedir. Bu derleme çalışmasında, rejeneratif endodontik tedavi yöntemi, kullanılan materyaller ve bu alandaki güncel gelişmeler detaylı olarak ele alınmaktadır.

 

Abstract

Withing the last 10 years, the research regarding stem cell biology and tissue engineering has reaped many rewards in the field of dentistry. The goal of regenerative endodontic therapy is the regeneration of a healthy and functional pulp-dentin complex. With the development of successful materials such as mineral trioxide aggregate (MTA) and the use of the concept of tissue engineering, treating necrotic immature permanent teeth and stimulating the continuation of root-surrounding tissue formation has been made possible. Current stem cell research has also shown promising results and continues to show progress in the regeneration of dental and surrounding tissue. Since the ethical aspect of the use of stem cells is still in question, we have yet to see the potential of these materials in clinical practice. In this review, regenerative endodontic treatment prodedures, materials and developments are discussed in detail.


Keywords


regenerative endodontics, dental pulp, pediatric dentistry

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References


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