Odontogenic cysts: A 40- year retrospective clinicopathological study in an Iranian population

Narges Ghazi, Nasrollah Saghravanian, Reza Zare-Mahmoodabadi, Saleh Hosseinpour
2.321 498

Abstract


We present a 40-year retrospective study of 1189 patients with odontogenic cysts (OCs) that were diagnosed from 1971 to 2011 in the Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Mashhad, Iran. In contrast to most of previous studies that have been reported inflammatory OCs as the most common type, in the current study, among cystic lesions of the jaws most were developmental in origin (62.30%). The most commonly diagnosed inflammatory and developmental odontogenic cysts were the periapical cyst (30.45%) and dentigerous cyst (26.80%) respectively. Developmental cysts were happened more in males whereas inflammatory types showed more tendency to females. The patients’ mean age was 27.20 ± 15.93 years, with a peak of occurrence in the second decade of life followed by the third decade. A high posterior mandibular incidence (41.85%) was observed, whereas some previous reports showed anterior maxilla predilection. The most common histological types of developmental cysts were aggressive (Dentigerous cyst, odontogenic keratocyst and calcifying odontogenic cyst). Furthermore, these three varieties representing more than half of all studied cysts (59.30%) at our Service. Knowledge of the incidence of odontogenic cysts and their clinicopatho­logic features, including most common location, gender and age distribution in different ethno-geographic backgrounds is necessary for the accurate diagnosis and differentiating aggressive lesions from other kinds of cysts .


Keywords


Odontogenic cyst, radicular cyst, dentigerous cyst, odontogenic keratocyst.

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References

Neville B.W , Damm D.D , Allen C.M , Bouquot J.E . Oral and maxillofacial pathology. WB Saunders Company, Philadelphia, 2009; p.678-701.

Salehinejad J , Saghafi S , Sharifi N , Zare-Mahmoodabadi R , Saghravanian N , Ghazi N, Shakeri MT. Evaluation of osteopontin and CD44v6 expression in odontogenic cystic lesions by immunohistochemistry. Pathol Res Pract 2012; 208: 410-14 .

Ochsenius G, Escobar E, Godoy L , Peñafiel C. Odontogenic cysts: analysis of 2,944 cases in Chile. Med Oral Patol Oral Cir Bucal 2007; 12: 85-91.

Kramer IR, Pindborg JJ, Shear M. The WHO Histological Typin of Odontogenic Tumours. A commentary on the Second Edition.Cancer. 1992; 70: 2988-94.

Buchner A. The central (intraosseous) calcifying odontogenic cyst: an analysis of 215 cases. J Oral Maxillofac Surg 1991; 49: 330-9.

Ioannidou F, Mustafa B, Seferiadou-Mavropoulou T.Odontogenic cysts of the jaws. A clinicostatistical study. Stomatologia (Athenai) 1989; 46 : 81-90.

Souza LB, Gordón-Núñez MA , Nonaka CF , de Medeiros MC , Torres TF, Emiliano GB. Odontogenic cysts: demographic profile in a Brazilian population over a 38-year period. Med Oral Patol Oral Cir Bucal 2010;15:583-90.

Sharifian MJ , Khalili M. Odontogenic cysts: a retrospective study of 1227 cases in an Irananian population from 1987 to 2007. J Oral Sci 2011; 53: 361-7.

Grossmann SM, Machado VC, Xavier GM, Moura MD, Gomez RS, Aguiar MC, Mesquita RA. Demographic profile of odontogenic and selected nonodontogenic cysts in a Brazilian population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 104: 35-41.

Servato JP, Prieto-Oliveira P, de Faria PR , Loyola AM. Odontogenic tumours: 240 cases diagnosed over 31 years at a Brazilian university and a review of international literature. Int J Oral Maxillofac Surg 2013; 42: 288-93.

Moctezuma-Bravo GS, Magallanes-González E. Study of 103 cases of odontogenic cysts. Rev Med Inst Mex Seguro Soc 200; 47 : 493-6.

CLedesma-Montes C, Hernández-Guerrero JC, Garcés-Ortíz M. Clinico-pathologic study of odontogenic cysts in a Mexican sample population. Arch Med Res 2000; 31: 373-6.

Meningaud JP, Oprean N, Pitak-Arnnop P, Bertrand JC. Odontogenic cysts: a clinical study of 695 cases. J Oral Sci 2006; 48: 59-62.

Bataineh AB, Rawashdeh MA, Al Qudah MA.The prevalence of inflammatory and developmental odontogenic cysts in a Jordanian population: a clinicopathologic study. Quintessence Int 2004;. 35: 815-9.

AV Jones AV, GT Craig GT, CD Franklin CD. Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period .J Oral Pathol Med 2006; 35 : 500-7.

Prockt AP, Schebela CR, Maito FD, Sant'Ana-Filho M, Rados PV. Odontogenic cysts: analysis of 680 cases in Brazil. Head Neck Pathol 2008; 2: 150-6.

El Gehani R, Krishnan B, Orafi H. The prevalence of inflammatory and developmental odontogenic cysts in a libyan population. Libyan J Med 2008; 3: 75-7.

Al Sheddi MA. Odontogenic cysts. A clinicopathological study. Saudi Med J 2012; 33: 304-8.

Butt FM, Ogeng’o J, Bahra J, ML Chindia ML. Pattern of odontogenic and nonodontogenic cysts. J Craniofac Surg 2011; 22: 1260-2.

Nuñez-Urrutia S, Figueiredo R, Gay-Escoda C. Retrospective clinicopathological study of 418 odontogenic cysts. Med Oral Patol Oral Cir Bucal 2010; 15: 767-73.

Tortorici S, Amodio E, Massenti MF, Buzzanca ML, Burruano F, Vitale F. Prevalence and distribution of odontogenic cysts in Sicily: 1986-2005. J Oral Sci 2008; 50: 15-8.

Arotiba JT, Lawoyin JO, Obiechina AE. Pattern of occurence of odontogenic cysts in Nigerians. East Afr Med J 1998; 75: 664-5.

Acikgoz A, Uzun-Bulut E, Ozden B, Gunduz K. Prevalence and distribution of odontogenic and non odontogenic cysts in Turkish population. Med Oral Patol Oral Cir Bucal 2012; 17: 108-15.

Paul J.W. Stoelinga .The management of aggeresive cysts of the jaw. J Maxillofac Oral Surg 2012; 11: 2-12.

Williams TP. Aggresive odontogenic cydrs and tumors . Oral Maxillofac Surg Clin N Am. 1997; 3: 329-38.

Metgud R, Gupta K. Expression of cell cycle and apoptosis-related proteins in ameloblastoma and keratocystic odontogenic tumor. Ann Diag Pathol 2013;17: 518–21.

Salehinejad J, Saghafi SH, Zare-Mahmoodabadi R, Ghazi N, Kermani H. Glandular Odontogenic Cyst of the Posterior Maxilla. Arch Iran Med 2011; 14:416-8.




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