Salmonella ishali olan immün yetmezlikli bir olguda oral immünoglobulin tedavisi

Fatma Duksal, Utku Aygüneş, Fatih Bolat, Mehmet Burhan Oflaz, Ömer Cevit
1.085 591

Abstract


Özet

Enfeksiyon ilişkili gastroenteritte en sık tanımlanan patojen virüslerden sonra salmonelladır. Salmonella’ya bağlı enfeksiyonlarda akut faz reaktanlarında artış ve ateş daha fazla görülmektedir. Salmonella enteropatojenik gram negatif basil olup lokalize enfeksiyondan sistemik enfeksiyona kadar değişen enfeksiyonlara yol açabilmektedir. En sık görülen şekli kendini sınırlayan komplike olmayan gastroenterittir. Rotavirüs ishali de Salmonella ishali gibi genel olarak kendini sınırladığı halde, bağışıklık sistemi baskılanmış hastalarda daha uzun ve ciddi seyredebilir. Daha çok rotavirüs ishallerinde yapılan çalışmalarda, verilen oral immünoglobulinin ishal süresini, semptomların şiddetini ve viral atılımı azalttığı gösterilmiştir. Salmonella ishalinde oral immünoglobilin verildiğini gösteren bir çalışmaya rastlamadık. Bu sunumda bağışıklık sistemi baskılanmış bir olguda Salmonella’ya bağlı ağır ishalin oral immünoglobulin ile tedavisi tartışılmıştır.

Anahtar sözcükler: İshal, Salmonella enfeksiyonları, oral immunoglobulin

 

Abstract

The most frequently identified pathogen, after viral pathogens, associated with infectious gastroenteritis is Salmonella. Increase in acute-phase reactants and fever are more frequently seen due to Salmonella infection. Salmonella, which is an enteropathogenic gram-negative bacilli causes infections ranging from localized to systemic infection. The most common form of Salmonella infection is uncomplicated self-limited gastroenteritis. In general, although rotavirus diarrhea like Salmonella diarrhea is limited by itself, it may cause a long and severe diarrhea in immunosuppressed patients. In the studies which have been done more with rotavirüs diarrhea, it was seen that, oral immunoglobulin reduced the severity of symptoms and of viral excretion. We did not find a study showing given oral immünogobilin in Salmonella diarrhea. In this presentation it is discussed oral immunoglobulin treatment in an immunosuppressed patient who had severe diarrhea due to Salmonella infection.

Keywords: Diarrhea, Salmonella infections, oral immunoglobulin


Keywords


Diarrhea, Salmonella infections, oral immunoglobulin

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